1uf4: Difference between revisions

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[[Image:1uf4.jpg|left|200px]]


{{Structure
==Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase==
|PDB= 1uf4 |SIZE=350|CAPTION= <scene name='initialview01'>1uf4</scene>, resolution 2.15&Aring;
<StructureSection load='1uf4' size='340' side='right'caption='[[1uf4]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1uf4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UF4 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/N-carbamoyl-D-amino_acid_hydrolase N-carbamoyl-D-amino acid hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.77 3.5.1.77]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uf4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uf4 OCA], [https://pdbe.org/1uf4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uf4 RCSB], [https://www.ebi.ac.uk/pdbsum/1uf4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uf4 ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase'''
[https://www.uniprot.org/uniprot/DCAS_AGRSK DCAS_AGRSK] The enzyme catalyzes the hydrolysis of N-carbamoyl-D-amino acids to the corresponding which are useful intermediates in the preparation of beta-lactam antibiotics. Industrial production of beta-lactam antibiotics is now being developed using this enzyme.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1UF4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Agrobacterium_sp. Agrobacterium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UF4 OCA].  
  <jmolCheckbox>
[[Category: Agrobacterium sp.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1uf4_consurf.spt"</scriptWhenChecked>
[[Category: N-carbamoyl-D-amino acid hydrolase]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Aoki, M.]]
  </jmolCheckbox>
[[Category: Hashimoto, H.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uf4 ConSurf].
[[Category: Ikenaka, Y.]]
<div style="clear:both"></div>
[[Category: Morikawa, H.]]
__TOC__
[[Category: Nakai, T.]]
</StructureSection>
[[Category: Sato, M.]]
[[Category: Agrobacterium sp]]
[[Category: Shimizu, T.]]
[[Category: Large Structures]]
[[Category: Takahashi, S.]]
[[Category: Aoki M]]
[[Category: d-amino acid]]
[[Category: Hashimoto H]]
[[Category: n-carbamyl-d-amino acid amidohydrolase]]
[[Category: Ikenaka Y]]
 
[[Category: Morikawa H]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:31:13 2008''
[[Category: Nakai T]]
[[Category: Sato M]]
[[Category: Shimizu T]]
[[Category: Takahashi S]]
Retrieved from "https://proteopedia.org/1uf4"