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[[Image:1v93.gif|left|200px]]


{{Structure
==5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8==
|PDB= 1v93 |SIZE=350|CAPTION= <scene name='initialview01'>1v93</scene>, resolution 1.90&Aring;
<StructureSection load='1v93' size='340' side='right'caption='[[1v93]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=DIO:1,4-DIETHYLENE DIOXIDE'>DIO</scene>
<table><tr><td colspan='2'>[[1v93]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V93 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V93 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Deleted_entry Deleted entry], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.7.99.5 1.7.99.5]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v93 OCA], [https://pdbe.org/1v93 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v93 RCSB], [https://www.ebi.ac.uk/pdbsum/1v93 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v93 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v93 TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9RA47_THETH Q9RA47_THETH]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v93_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v93 ConSurf].
<div style="clear:both"></div>


'''5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8'''
==See Also==
 
*[[Methylenetetrahydrofolate reductase 3D structures|Methylenetetrahydrofolate reductase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1V93 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V93 OCA].
[[Category: Large Structures]]
[[Category: Deleted entry]]
[[Category: Thermus thermophilus HB8]]
[[Category: Single protein]]
[[Category: Hirotsu K]]
[[Category: Thermus thermophilus]]
[[Category: Miyahara I]]
[[Category: Hirotsu, K.]]
[[Category: Nakajima Y]]
[[Category: Miyahara, I.]]
[[Category: Nakajima, Y.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: DIO]]
[[Category: FAD]]
[[Category: 10-methylenetetrahydrofolate reductase]]
[[Category: 5]]
[[Category: flavoprotein]]
[[Category: methylenetetrahydrofolate reductase]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:42:25 2008''

Latest revision as of 07:50, 25 October 2023

5,10-Methylenetetrahydrofolate Reductase from Thermus thermophilus HB8

1v93, resolution 1.90Å

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