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[[Image:1v94.gif|left|200px]]


{{Structure
==Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix==
|PDB= 1v94 |SIZE=350|CAPTION= <scene name='initialview01'>1v94</scene>, resolution 2.28&Aring;
<StructureSection load='1v94' size='340' side='right'caption='[[1v94]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1v94]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V94 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
|GENE= APE0689 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=56636 Aeropyrum pernix])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v94 OCA], [https://pdbe.org/1v94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v94 RCSB], [https://www.ebi.ac.uk/pdbsum/1v94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v94 ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9YE81_AERPE Q9YE81_AERPE]  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v94_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v94 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix'''
==See Also==
 
*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1V94 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V94 OCA].
 
==Reference==
Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix., Jeong JJ, Sonoda T, Fushinobu S, Shoun H, Wakagi T, Proteins. 2004 Jun 1;55(4):1087-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15146507 15146507]
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Isocitrate dehydrogenase (NADP(+))]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Fushinobu S]]
[[Category: Fushinobu, S.]]
[[Category: Jeong J-J]]
[[Category: Jeong, J J.]]
[[Category: Shoun H]]
[[Category: Shoun, H.]]
[[Category: Sonoda T]]
[[Category: Sonoda, T.]]
[[Category: Wakagi T]]
[[Category: Wakagi, T.]]
[[Category: 3 layer]]
[[Category: alpha/beta/alpha]]
[[Category: isocitrate dehydrogenase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:42:26 2008''

Latest revision as of 07:33, 30 October 2024

Crystal structure of isocitrate dehydrogenase from Aeropyrum pernix

1v94, resolution 2.28Å

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