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[[Image:1vs1.gif|left|200px]]


{{Structure
==Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP==
|PDB= 1vs1 |SIZE=350|CAPTION= <scene name='initialview01'>1vs1</scene>, resolution 2.30&Aring;
<StructureSection load='1vs1' size='340' side='right'caption='[[1vs1]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene> and <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>
<table><tr><td colspan='2'>[[1vs1]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VS1 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE= APE0581 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=56636 Aeropyrum pernix])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vs1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vs1 OCA], [https://pdbe.org/1vs1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vs1 RCSB], [https://www.ebi.ac.uk/pdbsum/1vs1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vs1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9YEJ7_AERPE Q9YEJ7_AERPE]  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/1vs1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vs1 ConSurf].
<div style="clear:both"></div>


'''Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from Aeropyrum pernix in complex with Mn2+ and PEP'''
==See Also==
 
*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1VS1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VS1 OCA].
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Aeropyrum pernix]]
[[Category: Aeropyrum pernix]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bauerle, R.]]
[[Category: Bauerle R]]
[[Category: Kretsinger, R H.]]
[[Category: Kretsinger RH]]
[[Category: Shumilin, I A.]]
[[Category: Shumilin IA]]
[[Category: Woodard, R W.]]
[[Category: Woodard RW]]
[[Category: Wu, J.]]
[[Category: Wu J]]
[[Category: Zhou, L.]]
[[Category: Zhou L]]
[[Category: MN]]
[[Category: PEP]]
[[Category: (beta/alpha)8 barrel]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:48:58 2008''
Retrieved from "https://proteopedia.org/1vs1"