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==Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger==
==Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger==
<StructureSection load='1mm0' size='340' side='right' caption='[[1mm0]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1mm0' size='340' side='right'caption='[[1mm0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mm0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudacanthotermes_spiniger Pseudacanthotermes spiniger]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MM0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mm0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudacanthotermes_spiniger Pseudacanthotermes spiniger]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MM0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MM0 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mm0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mm0 RCSB], [http://www.ebi.ac.uk/pdbsum/1mm0 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mm0 OCA], [https://pdbe.org/1mm0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mm0 RCSB], [https://www.ebi.ac.uk/pdbsum/1mm0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mm0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TERN_PSEUS TERN_PSEUS]] Weak activity against Gram-positive bacteria B.megaterium, S.pyogenes and M.luteus, strong activity against yeasts C.albicans, C.neoformans and S.cerevisiae and filamentous fungi F.oxysporum, F.culmorum, N.crassa and N.hematococca. Less active against filamentous fungus T.viride. Inactive against Gram-positive bacteria A.viridans and S.aureus, filamentous fungi A.fumigatus and B.bassiana and yeast C.glabrata.  
[https://www.uniprot.org/uniprot/TERN_PSEUS TERN_PSEUS] Weak activity against Gram-positive bacteria B.megaterium, S.pyogenes and M.luteus, strong activity against yeasts C.albicans, C.neoformans and S.cerevisiae and filamentous fungi F.oxysporum, F.culmorum, N.crassa and N.hematococca. Less active against filamentous fungus T.viride. Inactive against Gram-positive bacteria A.viridans and S.aureus, filamentous fungi A.fumigatus and B.bassiana and yeast C.glabrata.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mm/1mm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mm/1mm0_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mm0 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1mm0" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudacanthotermes spiniger]]
[[Category: Pseudacanthotermes spiniger]]
[[Category: Bulet, P]]
[[Category: Bulet P]]
[[Category: Caille, A]]
[[Category: Caille A]]
[[Category: Jouvensal, L]]
[[Category: Da Silva P]]
[[Category: Lamberty, M]]
[[Category: Jouvensal L]]
[[Category: Silva, P Da]]
[[Category: Lamberty M]]
[[Category: Vovelle, F]]
[[Category: Vovelle F]]
[[Category: Antimicrobial peptide]]
[[Category: Antimicrobial protein]]
[[Category: Csab motif]]
[[Category: Cytein-rich]]
[[Category: Insect defensin]]
[[Category: Termite]]

Latest revision as of 07:30, 23 October 2024

Solution structure of termicin, an antimicrobial peptide from the termite Pseudacanthotermes spiniger

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