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==Crystal Structure of D48V||A47D mutant of Human GLTP bound with 12:0 monosulfatide==
==Crystal Structure of D48V||A47D mutant of Human GLTP bound with 12:0 monosulfatide==
<StructureSection load='4ghp' size='340' side='right' caption='[[4ghp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='4ghp' size='340' side='right'caption='[[4ghp]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ghp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GHP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ghp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GHP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ric|3ric]], [[4gh0|4gh0]], [[4ghs|4ghs]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLTP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ghp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ghp OCA], [https://pdbe.org/4ghp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ghp RCSB], [https://www.ebi.ac.uk/pdbsum/4ghp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ghp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ghp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ghp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ghp RCSB], [http://www.ebi.ac.uk/pdbsum/4ghp PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN]] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>
[https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4ghp" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Malinina, L]]
[[Category: Large Structures]]
[[Category: Ochoa-Lizarralde, B]]
[[Category: Malinina L]]
[[Category: Popov, A N]]
[[Category: Ochoa-Lizarralde B]]
[[Category: Samygina, V R]]
[[Category: Popov AN]]
[[Category: Gltp-fold]]
[[Category: Samygina VR]]
[[Category: Lipid transport]]
Retrieved from "https://proteopedia.org/4ghp"