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[[Image:1wd7.gif|left|200px]]


{{Structure
==Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal)==
|PDB= 1wd7 |SIZE=350|CAPTION= <scene name='initialview01'>1wd7</scene>, resolution 1.60&Aring;
<StructureSection load='1wd7' size='340' side='right'caption='[[1wd7]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1wd7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WD7 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Uroporphyrinogen-III_synthase Uroporphyrinogen-III synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.75 4.2.1.75]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wd7 OCA], [https://pdbe.org/1wd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wd7 RCSB], [https://www.ebi.ac.uk/pdbsum/1wd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wd7 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wd7 TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal)'''
[https://www.uniprot.org/uniprot/Q5SKH2_THET8 Q5SKH2_THET8]
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1WD7 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WD7 OCA].  
  <jmolCheckbox>
[[Category: Protein complex]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wd/1wd7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wd7 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
[[Category: Uroporphyrinogen-III synthase]]
[[Category: Kuramitsu S]]
[[Category: Kuramitsu, S.]]
[[Category: Matsuura T]]
[[Category: Matsuura, T.]]
[[Category: Mizohata E]]
[[Category: Mizohata, E.]]
[[Category: Murayama K]]
[[Category: Murayama, K.]]
[[Category: Sakai H]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Shirouzu M]]
[[Category: Sakai, H.]]
[[Category: Terada T]]
[[Category: Shirouzu, M.]]
[[Category: Yokoyama S]]
[[Category: Terada, T.]]
[[Category: Yokoyama, S.]]
[[Category: congenital erythropoietic porphyria]]
[[Category: heme]]
[[Category: porphyrin]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: uroporphyrinogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:55:28 2008''

Latest revision as of 07:56, 25 October 2023

Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal)

1wd7, resolution 1.60Å

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