1wi0: Difference between revisions

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[[Image:1wi0.jpg|left|200px]]


{{Structure
==Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)==
|PDB= 1wi0 |SIZE=350|CAPTION= <scene name='initialview01'>1wi0</scene>
<StructureSection load='1wi0' size='340' side='right'caption='[[1wi0]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1wi0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WI0 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= RIKEN cDNA A230106F01 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [https://pdbe.org/1wi0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wi0 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/MP2K5_MOUSE MP2K5_MOUSE] Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.<ref>PMID:10473620</ref> <ref>PMID:16507987</ref>


'''Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)'''
==See Also==
 
*[[Mitogen-activated protein kinase kinase 3D structures|Mitogen-activated protein kinase kinase 3D structures]]
 
== References ==
==About this Structure==
<references/>
1WI0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Hayashi F]]
[[Category: Hayashi, F.]]
[[Category: Inoue M]]
[[Category: Inoue, M.]]
[[Category: Kigawa T]]
[[Category: Kigawa, T.]]
[[Category: Koshiba S]]
[[Category: Koshiba, S.]]
[[Category: Tochio N]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Tochio, N.]]
[[Category: Yoneyama M]]
[[Category: Yokoyama, S.]]
[[Category: Yoneyama, M.]]
[[Category: cytoplasmic signalling]]
[[Category: pb1 domain]]
[[Category: protein-protein interaction site]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
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Retrieved from "https://proteopedia.org/1wi0"