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[[Image:1wuh.gif|left|200px]]


{{Structure
==Three-Dimensional Structure Of The Ni-A State Of [Nife]Hydrogenase From Desulufovibrio Vulgaris Miyazaki F==
|PDB= 1wuh |SIZE=350|CAPTION= <scene name='initialview01'>1wuh</scene>, resolution 1.24&Aring;
<StructureSection load='1wuh' size='340' side='right'caption='[[1wuh]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=NFC:NI-FE+ACTIVE+CENTER+A-FORM'>NFC</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
<table><tr><td colspan='2'>[[1wuh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'Miyazaki_F' Desulfovibrio vulgaris str. 'Miyazaki F']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUH FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cytochrome-c3_hydrogenase Cytochrome-c3 hydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.12.2.1 1.12.2.1]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=NFC:NI-FE+ACTIVE+CENTER+A-FORM'>NFC</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wuh OCA], [https://pdbe.org/1wuh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wuh RCSB], [https://www.ebi.ac.uk/pdbsum/1wuh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wuh ProSAT]</span></td></tr>
 
</table>
'''Three-Dimensional Structure Of The Ni-A State Of [Nife]Hydrogenase From Desulufovibrio Vulgaris Miyazaki F'''
== Function ==
 
[https://www.uniprot.org/uniprot/PHNS_NITV9 PHNS_NITV9] Catalyzes the reversible oxidoreduction of molecular hydrogen, in conjunction with a specific electron acceptor, cytochrome c3.
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1WUH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris Desulfovibrio vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUH OCA].  
Check<jmol>
[[Category: Cytochrome-c3 hydrogenase]]
  <jmolCheckbox>
[[Category: Desulfovibrio vulgaris]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wuh_consurf.spt"</scriptWhenChecked>
[[Category: Protein complex]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Higuchi, Y.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Hirota, S.]]
  </jmolCheckbox>
[[Category: Kano, K.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wuh ConSurf].
[[Category: Kato, T.]]
<div style="clear:both"></div>
[[Category: Komori, H.]]
__TOC__
[[Category: Nakahara, A.]]
</StructureSection>
[[Category: Ogata, H.]]
[[Category: Desulfovibrio vulgaris str. 'Miyazaki F']]
[[Category: Shibata, N.]]
[[Category: Large Structures]]
[[Category: F3S]]
[[Category: Higuchi Y]]
[[Category: MG]]
[[Category: Hirota S]]
[[Category: MPD]]
[[Category: Kano K]]
[[Category: NFC]]
[[Category: Kato T]]
[[Category: SF4]]
[[Category: Komori H]]
[[Category: [nife]hydrogenase]]
[[Category: Nakahara A]]
[[Category: high resolution crystal structure]]
[[Category: Ogata H]]
[[Category: ni-a state]]
[[Category: Shibata N]]
[[Category: oxidoreductase]]
[[Category: unready state]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:01:43 2008''