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[[Image:1wye.gif|left|200px]]


{{Structure
==Crystal structure of 2-keto-3-deoxygluconate kinase (form 1) from Sulfolobus Tokodaii==
|PDB= 1wye |SIZE=350|CAPTION= <scene name='initialview01'>1wye</scene>, resolution 2.80&Aring;
<StructureSection load='1wye' size='340' side='right'caption='[[1wye]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[1wye]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WYE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WYE FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/2-dehydro-3-deoxygluconokinase 2-dehydro-3-deoxygluconokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.45 2.7.1.45]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wye FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wye OCA], [https://pdbe.org/1wye PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wye RCSB], [https://www.ebi.ac.uk/pdbsum/1wye PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wye ProSAT]</span></td></tr>
}}
</table>
 
== Function ==
'''Crystal structure of 2-keto-3-deoxygluconate kinase (form 1) from Sulfolobus Tokodaii'''
[https://www.uniprot.org/uniprot/KDGK_SULTO KDGK_SULTO] Involved in the degradation of glucose via the semi-phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Can also use GTP, but not ADP or AMP, as a phosphoryl donor and 2-keto-D-gluconate (KG) as a phosphoryl acceptor.<ref>PMID:17407821</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
1WYE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sulfolobus_tokodaii Sulfolobus tokodaii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WYE OCA].  
  <jmolCheckbox>
[[Category: 2-dehydro-3-deoxygluconokinase]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wy/1wye_consurf.spt"</scriptWhenChecked>
[[Category: Single protein]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Sulfolobus tokodaii]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Hossain, M T.]]
  </jmolCheckbox>
[[Category: Koike, I.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wye ConSurf].
[[Category: Sekiguchi, T.]]
<div style="clear:both"></div>
[[Category: Suzuki, K.]]
== References ==
[[Category: Takenaka, A.]]
<references/>
[[Category: Toyoda, T]]
__TOC__
[[Category: archea]]
</StructureSection>
[[Category: sulfolobus tokokai]]
[[Category: Large Structures]]
 
[[Category: Sulfurisphaera tokodaii str. 7]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:03:03 2008''
[[Category: Hossain MT]]
[[Category: Koike I]]
[[Category: Sekiguchi T]]
[[Category: Suzuki K]]
[[Category: Takenaka A]]
[[Category: Toyoda T]]
Retrieved from "https://proteopedia.org/1wye"