1x4m: Difference between revisions
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==Solution structure of KH domain in Far upstream element binding protein 1== | |||
<StructureSection load='1x4m' size='340' side='right'caption='[[1x4m]]' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1x4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X4M FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4m OCA], [https://pdbe.org/1x4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4m RCSB], [https://www.ebi.ac.uk/pdbsum/1x4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4m ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4m TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FUBP1_MOUSE FUBP1_MOUSE] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
== | Check<jmol> | ||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x4/1x4m_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x4m ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: He F]] | |||
[[Category: He | [[Category: Inoue M]] | ||
[[Category: Inoue | [[Category: Kigawa T]] | ||
[[Category: Kigawa | [[Category: Muto Y]] | ||
[[Category: Muto | [[Category: Shirouzu M]] | ||
[[Category: Terada T]] | |||
[[Category: Shirouzu | [[Category: Yokoyama S]] | ||
[[Category: Terada | |||
[[Category: Yokoyama | |||
Latest revision as of 13:58, 9 May 2024
Solution structure of KH domain in Far upstream element binding protein 1
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