2ly9: Difference between revisions
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==Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F== | ==Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F== | ||
<StructureSection load='2ly9' size='340' side='right' caption='[[2ly9 | <StructureSection load='2ly9' size='340' side='right'caption='[[2ly9]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ly9]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2ly9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY9 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly9 OCA], [https://pdbe.org/2ly9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ZHX1_HUMAN ZHX1_HUMAN] Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.<ref>PMID:12237128</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton | [[Category: Large Structures]] | ||
[[Category: Eletsky | [[Category: Acton TB]] | ||
[[Category: Everett | [[Category: Eletsky A]] | ||
[[Category: Janjua | [[Category: Everett JK]] | ||
[[Category: Kohan | [[Category: Janjua H]] | ||
[[Category: Lee | [[Category: Kohan E]] | ||
[[Category: Mills | [[Category: Lee D]] | ||
[[Category: Montelione | [[Category: Mills JL]] | ||
[[Category: Montelione GT]] | |||
[[Category: Pulavarti | [[Category: Pulavarti SVSRK]] | ||
[[Category: Szyperski | [[Category: Szyperski T]] | ||
[[Category: Xiao | [[Category: Xiao R]] | ||
[[Category: Xu | [[Category: Xu X]] | ||