2r88: Difference between revisions

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==Crystal structure of the long-chain fatty acid transporter FadL mutant delta S3 kink==
==Crystal structure of the long-chain fatty acid transporter FadL mutant delta S3 kink==
<StructureSection load='2r88' size='340' side='right' caption='[[2r88]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2r88' size='340' side='right'caption='[[2r88]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r88]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R88 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2R88 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2r88]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R88 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R88 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t16|1t16]], [[1t1l|1t1l]], [[2r4l|2r4l]], [[2r4m|2r4m]], [[2r4n|2r4n]], [[2r4o|2r4o]], [[2r4p|2r4p]], [[2r89|2r89]], [[2r8a|2r8a]], [[3dwo|3dwo]], [[3dwn|3dwn]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fadL, ttr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r88 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r88 OCA], [https://pdbe.org/2r88 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r88 RCSB], [https://www.ebi.ac.uk/pdbsum/2r88 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r88 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r88 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r88 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r88 RCSB], [http://www.ebi.ac.uk/pdbsum/2r88 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FADL_ECOLI FADL_ECOLI]] Involved in translocation of long-chain fatty acids across the outer membrane. It is a receptor for the bacteriophage T2. FadL may form a specific channel.  
[https://www.uniprot.org/uniprot/FADL_ECOLI FADL_ECOLI] Involved in translocation of long-chain fatty acids across the outer membrane. It is a receptor for the bacteriophage T2. FadL may form a specific channel.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r88_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r8/2r88_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r88 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2r88" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Berg, B van den]]
[[Category: Large Structures]]
[[Category: Hearn, E M]]
[[Category: Hearn EM]]
[[Category: Indic, M]]
[[Category: Indic M]]
[[Category: Lepore, B W]]
[[Category: Lepore BW]]
[[Category: Patel, D R]]
[[Category: Patel DR]]
[[Category: Beta barrel]]
[[Category: Van den Berg B]]
[[Category: Lipid transport]]
[[Category: Outer membrane protein]]
[[Category: Phage recognition]]
[[Category: Transmembrane]]
[[Category: Transport]]
[[Category: Transport protein]]
Retrieved from "https://proteopedia.org/2r88"