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==Crystal structure of the triscatecholate siderophore binding protein FeuA from Bacillus subtilis complexed with Ferric MECAM==
==Crystal structure of the triscatecholate siderophore binding protein FeuA from Bacillus subtilis complexed with Ferric MECAM==
<StructureSection load='2xv1' size='340' side='right' caption='[[2xv1]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='2xv1' size='340' side='right'caption='[[2xv1]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xv1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XV1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XV1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xv1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XV1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ECA:N,N,N-[BENZENE-1,3,5-TRIYLTRIS(METHYLENE)]TRIS(2,3-DIHYDROXYBENZAMIDE)'>ECA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2why|2why]], [[2xuz|2xuz]], [[2wi8|2wi8]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ECA:N,N,N-[BENZENE-1,3,5-TRIYLTRIS(METHYLENE)]TRIS(2,3-DIHYDROXYBENZAMIDE)'>ECA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xv1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xv1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xv1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xv1 OCA], [https://pdbe.org/2xv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xv1 RCSB], [https://www.ebi.ac.uk/pdbsum/2xv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xv1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FEUA_BACSU FEUA_BACSU]] Involved in the uptake of iron.<ref>PMID:16672620</ref>  Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable).<ref>PMID:16672620</ref>
[https://www.uniprot.org/uniprot/FEUA_BACSU FEUA_BACSU] Involved in the uptake of iron.<ref>PMID:16672620</ref>  Part of the ABC transporter complex FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable).<ref>PMID:16672620</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2xv1" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Albrecht, A G]]
[[Category: Large Structures]]
[[Category: Marahiel, M A]]
[[Category: Albrecht AG]]
[[Category: Miethke, M]]
[[Category: Marahiel MA]]
[[Category: Oberthuer, M]]
[[Category: Miethke M]]
[[Category: Peuckert, F]]
[[Category: Oberthuer M]]
[[Category: Schwoerer, C J]]
[[Category: Peuckert F]]
[[Category: Bacillibactin and enterobactin binding]]
[[Category: Schwoerer CJ]]
[[Category: High affinity iron import]]
[[Category: Iron transport]]
[[Category: Transport protein]]

Latest revision as of 10:39, 20 December 2023

Crystal structure of the triscatecholate siderophore binding protein FeuA from Bacillus subtilis complexed with Ferric MECAM

2xv1, resolution 2.15Å

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