4ua1: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4ua1 is ON HOLD  until Paper Publication
==Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion==
<StructureSection load='4ua1' size='340' side='right'caption='[[4ua1]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ua1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UA1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ua1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ua1 OCA], [https://pdbe.org/4ua1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ua1 RCSB], [https://www.ebi.ac.uk/pdbsum/4ua1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ua1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q799U3_PRIMG Q799U3_PRIMG] Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.[ARBA:ARBA00024874]


Authors: Chang, C.C., Lin, L.Y., Zou, X.W., Huang, C.C., Chan, N.L.
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
Description: Crystal structure of dual function transcriptional regulator MerR form Bacillus megaterium MB1 in complex with mercury (II) ion
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Chang, C.C]]
[[Category: Large Structures]]
[[Category: Huang, C.C]]
[[Category: Priestia megaterium]]
[[Category: Chan, N.L]]
[[Category: Chan NL]]
[[Category: Lin, L.Y]]
[[Category: Chang CC]]
[[Category: Zou, X.W]]
[[Category: Huang CC]]
[[Category: Lin LY]]
[[Category: Zou XW]]