4wyo: Difference between revisions

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'''Unreleased structure'''


The entry 4wyo is ON HOLD
==Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1==
<StructureSection load='4wyo' size='340' side='right'caption='[[4wyo]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4wyo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WYO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WYO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.89&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3W2:2-TERT-BUTYL-1-(2H-INDAZOL-5-YLCARBONYL)-2H-SPIRO[PIPERIDINE-4,5-PYRANO[3,2-C]PYRAZOL]-7(6H)-ONE'>3W2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wyo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wyo OCA], [https://pdbe.org/4wyo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wyo RCSB], [https://www.ebi.ac.uk/pdbsum/4wyo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wyo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACAC_YEAST ACAC_YEAST] Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nuclear envelope. Required for acylation and vacuolar membrane association of VAC8 which is necessary to maintain a normal morphology of the vacuole.<ref>PMID:6108218</ref> <ref>PMID:6103540</ref> <ref>PMID:8943372</ref> <ref>PMID:10757783</ref> <ref>PMID:12730220</ref>


Authors: Vajdos, F.F.
==See Also==
 
*[[Acetyl-CoA carboxylase 3D structures|Acetyl-CoA carboxylase 3D structures]]
Description: Crystal structure of human-yeast chimera acetyl coA carboxylase CT domain bound to Compound 1
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Vajdos, F.F]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Vajdos FF]]
Retrieved from "https://proteopedia.org/4wyo"