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New page: left|200px<br /> <applet load="1e5e" size="450" color="white" frame="true" align="right" spinBox="true" caption="1e5e, resolution 2.18Å" /> '''METHIONINE GAMMA-LY...
 
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[[Image:1e5e.gif|left|200px]]<br />
<applet load="1e5e" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1e5e, resolution 2.18&Aring;" />
'''METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE'''<br />


==About this Structure==
==METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE==
1E5E is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]] with SO4, PPJ and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA]].
<StructureSection load='1e5e' size='340' side='right'caption='[[1e5e]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Trichomonas vaginalis]]
<table><tr><td colspan='2'>[[1e5e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis_G3 Trichomonas vaginalis G3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5E FirstGlance]. <br>
[[Category: Coombs, G.H.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
[[Category: Goodall, G.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PPJ:N-(HYDROXY{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)NORVALINE'>PPJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Lapthorn, A.J.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5e OCA], [https://pdbe.org/1e5e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5e RCSB], [https://www.ebi.ac.uk/pdbsum/1e5e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5e ProSAT]</span></td></tr>
[[Category: Mottram, J.C.]]
</table>
[[Category: GOL]]
== Function ==
[[Category: PPJ]]
[https://www.uniprot.org/uniprot/A2FEV4_TRIV3 A2FEV4_TRIV3]  
[[Category: SO4]]
== Evolutionary Conservation ==
[[Category: c-s gamma lyase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: plp-dependent enzymes]]
Check<jmol>
[[Category: propargylglycine]]
  <jmolCheckbox>
[[Category: trichomonas vaginalis]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5e ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 16:54:27 2007''
==See Also==
*[[Methionine gamma-lyase 3D structures|Methionine gamma-lyase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trichomonas vaginalis G3]]
[[Category: Coombs GH]]
[[Category: Goodall G]]
[[Category: Lapthorn AJ]]
[[Category: Mottram JC]]

Latest revision as of 11:53, 13 December 2023

METHIONINE GAMMA-LYASE (MGL) FROM TRICHOMONAS VAGINALIS IN COMPLEX WITH PROPARGYLGLYCINE

1e5e, resolution 2.18Å

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