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==Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5==
==Crystal structure of Streptococcus pyogenes Cas2 at pH 7.5==
<StructureSection load='4qr2' size='340' side='right' caption='[[4qr2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='4qr2' size='340' side='right'caption='[[4qr2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4qr2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QR2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4qr2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_serotype_M1 Streptococcus pyogenes serotype M1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QR2 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4qr0|4qr0]], [[4qr1|4qr1]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qr2 RCSB], [http://www.ebi.ac.uk/pdbsum/4qr2 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qr2 OCA], [https://pdbe.org/4qr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qr2 RCSB], [https://www.ebi.ac.uk/pdbsum/4qr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qr2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q99YS8_STRP1 Q99YS8_STRP1]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471]  
[https://www.uniprot.org/uniprot/Q99YS8_STRP1 Q99YS8_STRP1] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.[HAMAP-Rule:MF_01471]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4qr2" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bae, E]]
[[Category: Large Structures]]
[[Category: Ka, D]]
[[Category: Streptococcus pyogenes serotype M1]]
[[Category: Kim, D]]
[[Category: Bae E]]
[[Category: Deoxyribonuclease]]
[[Category: Ka D]]
[[Category: Ferredoxin-like fold]]
[[Category: Kim D]]
[[Category: Hydrolase]]
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