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==Crystal structure of Type IIF restriction endonuclease NgoMIV with cognate uncleaved DNA==
==Crystal structure of Type IIF restriction endonuclease NgoMIV with cognate uncleaved DNA==
<StructureSection load='4abt' size='340' side='right' caption='[[4abt]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
<StructureSection load='4abt' size='340' side='right'caption='[[4abt]], [[Resolution|resolution]] 2.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4abt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ABT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4abt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ABT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ABT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fiu|1fiu]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4abt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abt OCA], [https://pdbe.org/4abt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4abt RCSB], [https://www.ebi.ac.uk/pdbsum/4abt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4abt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4abt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4abt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4abt RCSB], [http://www.ebi.ac.uk/pdbsum/4abt PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/T2M4_NEIGO T2M4_NEIGO]] Recognizes the double-stranded sequence GCCGGC and cleaves after G-1.  
[https://www.uniprot.org/uniprot/T2M4_NEIGO T2M4_NEIGO] Recognizes the double-stranded sequence GCCGGC and cleaves after G-1.


==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Neisseria gonorrhoeae]]
[[Category: Neisseria gonorrhoeae]]
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Golovenko D]]
[[Category: Golovenko, D]]
[[Category: Grazulis S]]
[[Category: Grazulis, S]]
[[Category: Manakova EN]]
[[Category: Manakova, E N]]
[[Category: Siksnys V]]
[[Category: Siksnys, V]]
[[Category: Tamulaitiene G]]
[[Category: Tamulaitiene, G]]
[[Category: Zaremba M]]
[[Category: Zaremba, M]]
[[Category: Hydrolase-dna complex]]
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