3a57: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Crystal structure of Thermostable Direct Hemolysin==
==Crystal structure of Thermostable Direct Hemolysin==
<StructureSection load='3a57' size='340' side='right' caption='[[3a57]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='3a57' size='340' side='right'caption='[[3a57]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a57]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_parahaemolyticus Vibrio parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A57 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_parahaemolyticus Vibrio parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A57 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tdh ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=670 Vibrio parahaemolyticus])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a57 RCSB], [http://www.ebi.ac.uk/pdbsum/3a57 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a57 OCA], [https://pdbe.org/3a57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a57 RCSB], [https://www.ebi.ac.uk/pdbsum/3a57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a57 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HLY2_VIBPA HLY2_VIBPA]] Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.  
[https://www.uniprot.org/uniprot/HLY2_VIBPA HLY2_VIBPA] Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/3a57_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/3a57_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a57 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 26: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3a57" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Hemolysin|Hemolysin]]
*[[Hemolysin 3D structures|Hemolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio parahaemolyticus]]
[[Category: Vibrio parahaemolyticus]]
[[Category: Fukui, T]]
[[Category: Fukui T]]
[[Category: Hamada, D]]
[[Category: Hamada D]]
[[Category: Hashimoto, H]]
[[Category: Hashimoto H]]
[[Category: Honda, T]]
[[Category: Honda T]]
[[Category: Ikegami, T]]
[[Category: Ikegami T]]
[[Category: Ikeguchi, M]]
[[Category: Ikeguchi M]]
[[Category: Kaieda, S]]
[[Category: Kaieda S]]
[[Category: Kajiyama, S]]
[[Category: Kajiyama S]]
[[Category: Mayanagi, K]]
[[Category: Mayanagi K]]
[[Category: Nakahira, K]]
[[Category: Nakahira K]]
[[Category: Ohnishi, K]]
[[Category: Ohnishi K]]
[[Category: Sato, M]]
[[Category: Sato M]]
[[Category: Shimizu, T]]
[[Category: Shimizu T]]
[[Category: Yamane, T]]
[[Category: Yamane T]]
[[Category: Yanagihara, I]]
[[Category: Yanagihara I]]
[[Category: Cytolysis]]
[[Category: Disulfide bond]]
[[Category: Hemolysin]]
[[Category: Hemolysis]]
[[Category: Toxin]]