3a57: Difference between revisions
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==Crystal structure of Thermostable Direct Hemolysin== | ==Crystal structure of Thermostable Direct Hemolysin== | ||
<StructureSection load='3a57' size='340' side='right' caption='[[3a57]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='3a57' size='340' side='right'caption='[[3a57]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3a57]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3a57]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_parahaemolyticus Vibrio parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A57 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A57 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a57 OCA], [https://pdbe.org/3a57 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a57 RCSB], [https://www.ebi.ac.uk/pdbsum/3a57 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a57 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HLY2_VIBPA HLY2_VIBPA] Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/3a57_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a5/3a57_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a57 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3a57" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Hemolysin|Hemolysin]] | *[[Hemolysin 3D structures|Hemolysin 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Vibrio parahaemolyticus]] | [[Category: Vibrio parahaemolyticus]] | ||
[[Category: Fukui | [[Category: Fukui T]] | ||
[[Category: Hamada | [[Category: Hamada D]] | ||
[[Category: Hashimoto | [[Category: Hashimoto H]] | ||
[[Category: Honda | [[Category: Honda T]] | ||
[[Category: Ikegami | [[Category: Ikegami T]] | ||
[[Category: Ikeguchi | [[Category: Ikeguchi M]] | ||
[[Category: Kaieda | [[Category: Kaieda S]] | ||
[[Category: Kajiyama | [[Category: Kajiyama S]] | ||
[[Category: Mayanagi | [[Category: Mayanagi K]] | ||
[[Category: Nakahira | [[Category: Nakahira K]] | ||
[[Category: Ohnishi | [[Category: Ohnishi K]] | ||
[[Category: Sato | [[Category: Sato M]] | ||
[[Category: Shimizu | [[Category: Shimizu T]] | ||
[[Category: Yamane | [[Category: Yamane T]] | ||
[[Category: Yanagihara | [[Category: Yanagihara I]] | ||