2a3s: Difference between revisions

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[[Image:2a3s.gif|left|200px]]


{{Structure
==Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor==
|PDB= 2a3s |SIZE=350|CAPTION= <scene name='initialview01'>2a3s</scene>
<StructureSection load='2a3s' size='340' side='right'caption='[[2a3s]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2a3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A3S FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= Foxk1(AMINO ACID 287-387) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a3s OCA], [https://pdbe.org/2a3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a3s RCSB], [https://www.ebi.ac.uk/pdbsum/2a3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a3s ProSAT]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/FOXK1_MOUSE FOXK1_MOUSE] Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.<ref>PMID:8007964</ref> <ref>PMID:9271401</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/2a3s_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a3s ConSurf].
<div style="clear:both"></div>


'''Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor'''
==See Also==
 
*[[FOX 3D structures|FOX 3D structures]]
 
== References ==
==About this Structure==
<references/>
2A3S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A3S OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Chang C-H]]
[[Category: Chang, C H.]]
[[Category: Chu Y-P]]
[[Category: Chu, Y P.]]
[[Category: Chuang W-J]]
[[Category: Chuang, W J.]]
[[Category: Jeng W-Y]]
[[Category: Jeng, W Y.]]
[[Category: dna-binding domain]]
[[Category: forkhead]]
[[Category: nmr]]
[[Category: winged-helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:45:01 2008''

Latest revision as of 08:15, 15 May 2024

Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor

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