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==Crystal Structure of Bovine Serum Albumin in complex with naproxen==
==Crystal Structure of Bovine Serum Albumin in complex with naproxen==
<StructureSection load='4or0' size='340' side='right' caption='[[4or0]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
<StructureSection load='4or0' size='340' side='right'caption='[[4or0]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4or0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OR0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OR0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4or0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OR0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NPS:(2S)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC+ACID'>NPS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4f5s|4f5s]], [[4jk4|4jk4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NPS:(2S)-2-(6-METHOXYNAPHTHALEN-2-YL)PROPANOIC+ACID'>NPS</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4or0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4or0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4or0 RCSB], [http://www.ebi.ac.uk/pdbsum/4or0 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4or0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4or0 OCA], [https://pdbe.org/4or0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4or0 RCSB], [https://www.ebi.ac.uk/pdbsum/4or0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4or0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.  
[https://www.uniprot.org/uniprot/ALBU_BOVIN ALBU_BOVIN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4or0" style="background-color:#fffaf0;"></div>
==See Also==
*[[Albumin 3D structures|Albumin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Bujacz, A]]
[[Category: Large Structures]]
[[Category: Bujacz, G]]
[[Category: Bujacz A]]
[[Category: Sekula, B]]
[[Category: Bujacz G]]
[[Category: Zielinski, K]]
[[Category: Sekula B]]
[[Category: Bovine serum albumin]]
[[Category: Zielinski K]]
[[Category: Bsa]]
[[Category: Drug]]
[[Category: Fatty acid]]
[[Category: Helical protein possessing three domain]]
[[Category: Hormone]]
[[Category: Metabolite]]
[[Category: Naproxen]]
[[Category: Plasma]]
[[Category: Transport protein]]
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