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==NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE==
==NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE==
<StructureSection load='1vih' size='340' side='right' caption='[[1vih]], [[NMR_Ensembles_of_Models | 1 NMR models]]' scene=''>
<StructureSection load='1vih' size='340' side='right'caption='[[1vih]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vih]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VIH FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vih]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VIH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vig|1vig]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMAN VIGILIN SIXTH KH REPEAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vih OCA], [https://pdbe.org/1vih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vih RCSB], [https://www.ebi.ac.uk/pdbsum/1vih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vih ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vih OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vih RCSB], [http://www.ebi.ac.uk/pdbsum/1vih PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/VIGLN_HUMAN VIGLN_HUMAN]] Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.  
[https://www.uniprot.org/uniprot/VIGLN_HUMAN VIGLN_HUMAN] Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vi/1vih_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vi/1vih_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vih ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 1vih" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Gibson, T J]]
[[Category: Large Structures]]
[[Category: Joseph, C]]
[[Category: Gibson TJ]]
[[Category: Morelli, M A.C]]
[[Category: Joseph C]]
[[Category: Musco, G]]
[[Category: Morelli MAC]]
[[Category: Nilges, M]]
[[Category: Musco G]]
[[Category: Pastore, A]]
[[Category: Nilges M]]
[[Category: Stier, G]]
[[Category: Pastore A]]
[[Category: Ribonucleoprotein]]
[[Category: Stier G]]
[[Category: Rna-binding protein]]

Latest revision as of 13:25, 9 May 2024

NMR STUDY OF VIGILIN, REPEAT 6, MINIMIZED AVERAGE STRUCTURE

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