4afx: Difference between revisions

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==Crystal structure of the reactive loop cleaved ZPI in I2 space group==
==Crystal structure of the reactive loop cleaved ZPI in I2 space group==
<StructureSection load='4afx' size='340' side='right' caption='[[4afx]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
<StructureSection load='4afx' size='340' side='right'caption='[[4afx]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4afx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AFX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4afx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AFX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4aju|4aju]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4afx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4afx RCSB], [http://www.ebi.ac.uk/pdbsum/4afx PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4afx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4afx OCA], [https://pdbe.org/4afx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4afx RCSB], [https://www.ebi.ac.uk/pdbsum/4afx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4afx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZPI_HUMAN ZPI_HUMAN]] Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids.  
[https://www.uniprot.org/uniprot/ZPI_HUMAN ZPI_HUMAN] Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4afx" style="background-color:#fffaf0;"></div>
==See Also==
*[[Serpin 3D structures|Serpin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Wei, Z]]
[[Category: Large Structures]]
[[Category: Yan, Y]]
[[Category: Wei Z]]
[[Category: Zhou, A]]
[[Category: Yan Y]]
[[Category: Coagulation]]
[[Category: Zhou A]]
[[Category: Hydrolase inhibitor]]
[[Category: Protein z dependent inhibitor]]
[[Category: Serpin]]

Latest revision as of 11:26, 20 December 2023

Crystal structure of the reactive loop cleaved ZPI in I2 space group

4afx, resolution 2.09Å

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