2b60: Difference between revisions
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==Structure of HIV-1 protease mutant bound to Ritonavir== | |||
<StructureSection load='2b60' size='340' side='right'caption='[[2b60]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2b60]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B60 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b60 OCA], [https://pdbe.org/2b60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b60 RCSB], [https://www.ebi.ac.uk/pdbsum/2b60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b60 ProSAT]</span></td></tr> | |||
</table> | |||
'' | == Function == | ||
[https://www.uniprot.org/uniprot/Q7SMT3_9HIV1 Q7SMT3_9HIV1] | |||
== Evolutionary Conservation == | |||
== | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b60_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b60 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Agbandje-McKenna | [[Category: Agbandje-McKenna M]] | ||
[[Category: Clemente | [[Category: Clemente JC]] | ||
[[Category: Desai | [[Category: Desai KA]] | ||
[[Category: Dunn | [[Category: Dunn BM]] | ||
[[Category: Goodenow | [[Category: Goodenow MM]] | ||
[[Category: Govindasamy | [[Category: Govindasamy L]] | ||
[[Category: Janka | [[Category: Janka LK]] | ||
[[Category: Jeung | [[Category: Jeung JA]] | ||
[[Category: McKenna | [[Category: McKenna R]] | ||
[[Category: Stow | [[Category: Stow LR]] | ||
