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[[Image:2b69.gif|left|200px]]


{{Structure
==Crystal Structure of Human UDP-glucoronic acid decarboxylase==
|PDB= 2b69 |SIZE=350|CAPTION= <scene name='initialview01'>2b69</scene>, resolution 1.21&Aring;
<StructureSection load='2b69' size='340' side='right'caption='[[2b69]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=UDP:URIDINE-5'-DIPHOSPHATE'>UDP</scene>
<table><tr><td colspan='2'>[[2b69]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B69 FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/UDP-glucuronate_decarboxylase UDP-glucuronate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.35 4.1.1.35]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
|GENE= UXS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b69 OCA], [https://pdbe.org/2b69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b69 RCSB], [https://www.ebi.ac.uk/pdbsum/2b69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b69 ProSAT]</span></td></tr>
 
</table>
'''Crystal Structure of Human UDP-glucoronic acid decarboxylase'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
2B69 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B69 OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b69_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b69 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: UDP-glucuronate decarboxylase]]
[[Category: Arrowsmith C]]
[[Category: Arrowsmith, C.]]
[[Category: Dubinina E]]
[[Category: Delft, F von.]]
[[Category: Edwards A]]
[[Category: Dubinina, E.]]
[[Category: Kavanagh K]]
[[Category: Edwards, A.]]
[[Category: Oppermann U]]
[[Category: Kavanagh, K.]]
[[Category: Sundstrom M]]
[[Category: Oppermann, U.]]
[[Category: Ugochukwu E]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Weigelt J]]
[[Category: Sundstrom, M.]]
[[Category: Von Delft F]]
[[Category: Ugochukwu, E.]]
[[Category: Weigelt, J.]]
[[Category: NAD]]
[[Category: UDP]]
[[Category: sgc]]
[[Category: structural genomic]]
[[Category: structural genomics consortium]]
[[Category: udp-glucoronic acid decarboxylase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:58:05 2008''

Latest revision as of 00:48, 21 November 2024

Crystal Structure of Human UDP-glucoronic acid decarboxylase

2b69, resolution 1.21Å

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