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==Crystal Structure of EC1530, a Putative Oxygenase from Escherichia coli==
==Crystal Structure of EC1530, a Putative Oxygenase from Escherichia coli==
<StructureSection load='1k77' size='340' side='right' caption='[[1k77]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
<StructureSection load='1k77' size='340' side='right'caption='[[1k77]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1k77]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K77 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1k77]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K77 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k77 RCSB], [http://www.ebi.ac.uk/pdbsum/1k77 PDBsum], [http://www.topsan.org/Proteins/MCSG/1k77 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k77 OCA], [https://pdbe.org/1k77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k77 RCSB], [https://www.ebi.ac.uk/pdbsum/1k77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k77 ProSAT], [https://www.topsan.org/Proteins/MCSG/1k77 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/YGBM_ECOLI YGBM_ECOLI]] Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity).  
[https://www.uniprot.org/uniprot/OTNI_ECOLI OTNI_ECOLI] Catalyzes the isomerization of 2-oxo-tetronate to 3-oxo-tetronate.[UniProtKB:Q57151]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/1k77_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k7/1k77_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k77 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Arrowsmith, C H]]
[[Category: Large Structures]]
[[Category: Beasley, S]]
[[Category: Arrowsmith CH]]
[[Category: Edwards, A M]]
[[Category: Beasley S]]
[[Category: Joachimiak, A]]
[[Category: Edwards AM]]
[[Category: Kim, Y]]
[[Category: Joachimiak A]]
[[Category: Laskowski, R]]
[[Category: Kim Y]]
[[Category: Structural genomic]]
[[Category: Laskowski R]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Skarina, T]]
[[Category: Skarina T]]
[[Category: Hypothetical protein]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tim barrel]]
[[Category: Unknown function]]

Latest revision as of 07:58, 3 April 2024

Crystal Structure of EC1530, a Putative Oxygenase from Escherichia coli

1k77, resolution 1.63Å

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