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==The crystal structure of Tp34 bound to Co (II) ion at pH 7.5==
==The crystal structure of Tp34 bound to Co (II) ion at pH 7.5==
<StructureSection load='3pjl' size='340' side='right' caption='[[3pjl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3pjl' size='340' side='right'caption='[[3pjl]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pjl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PJL FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pjl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Treponema_pallidum Treponema pallidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2o6f|2o6f]], [[2o6c|2o6c]], [[2o6d|2o6d]], [[2o6e|2o6e]], [[3pjo|3pjo]], [[3pjm|3pjm]], [[3pjn|3pjn]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tpd, TP_0971 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=160 Treponema pallidum])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjl OCA], [https://pdbe.org/3pjl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pjl RCSB], [https://www.ebi.ac.uk/pdbsum/3pjl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pjl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pjl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pjl RCSB], [http://www.ebi.ac.uk/pdbsum/3pjl PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TA34_TREPA TA34_TREPA]] This antigen is a pathogen-specific membrane immunogen.  
[https://www.uniprot.org/uniprot/TA34_TREPA TA34_TREPA] This antigen is a pathogen-specific membrane immunogen.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Treponema pallidum]]
[[Category: Treponema pallidum]]
[[Category: Brautigam, C A]]
[[Category: Brautigam CA]]
[[Category: Deka, R K]]
[[Category: Deka RK]]
[[Category: Machius, M]]
[[Category: Machius M]]
[[Category: Norgard, M V]]
[[Category: Norgard MV]]
[[Category: Tomchick, D R]]
[[Category: Tomchick DR]]
[[Category: Human lactoferrin]]
[[Category: Ig fold]]
[[Category: Membrane protein]]
[[Category: Metal binding]]

Latest revision as of 10:41, 21 February 2024

The crystal structure of Tp34 bound to Co (II) ion at pH 7.5

3pjl, resolution 1.70Å

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