2kro: Difference between revisions
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==RDC refined high resolution structure of the third SH3 domain of CD2AP== | ==RDC refined high resolution structure of the third SH3 domain of CD2AP== | ||
<StructureSection load='2kro' size='340' side='right' caption='[[2kro | <StructureSection load='2kro' size='340' side='right'caption='[[2kro]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2kro]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2kro]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRO FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kro OCA], [https://pdbe.org/2kro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kro RCSB], [https://www.ebi.ac.uk/pdbsum/2kro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kro ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CD2AP_MOUSE CD2AP_MOUSE] Required for cytokinesis (By similarity). Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus.<ref>PMID:10514378</ref> | ||
==See Also== | ==See Also== | ||
*[[CD2-associated protein|CD2-associated protein]] | *[[CD2-associated protein 3D structures|CD2-associated protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Azuaga | [[Category: Azuaga AI]] | ||
[[Category: Blackledge | [[Category: Blackledge M]] | ||
[[Category: | [[Category: Ortega Roldan J]] | ||
[[Category: Van Nuland NAJ]] | |||
[[Category: | |||
Latest revision as of 06:48, 1 May 2024
RDC refined high resolution structure of the third SH3 domain of CD2AP
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