4q10: Difference between revisions

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==The catalytic core of Rad2 in complex with DNA substrate (complex IV)==
==The catalytic core of Rad2 in complex with DNA substrate (complex IV)==
<StructureSection load='4q10' size='340' side='right' caption='[[4q10]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4q10' size='340' side='right'caption='[[4q10]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4q10]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q10 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q10 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4q10]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q10 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0w|4q0w]], [[4q0z|4q0z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q10 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q10 RCSB], [http://www.ebi.ac.uk/pdbsum/4q10 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q10 OCA], [https://pdbe.org/4q10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q10 RCSB], [https://www.ebi.ac.uk/pdbsum/4q10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q10 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RAD2_YEAST RAD2_YEAST]] Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.<ref>PMID:8247134</ref>
[https://www.uniprot.org/uniprot/RAD2_YEAST RAD2_YEAST] Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.<ref>PMID:8247134</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4q10" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Jaciuk, M]]
[[Category: Large Structures]]
[[Category: Kustosz, P]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Mietus, M]]
[[Category: Jaciuk M]]
[[Category: Nowak, E]]
[[Category: Kustosz P]]
[[Category: Nowotny, M]]
[[Category: Mietus M]]
[[Category: Ba rossmann-like]]
[[Category: Nowak E]]
[[Category: Dna repair]]
[[Category: Nowotny M]]
[[Category: Hydrolase-dna complex]]
[[Category: Nucleus]]
[[Category: Tfiih]]

Latest revision as of 17:26, 20 September 2023

The catalytic core of Rad2 in complex with DNA substrate (complex IV)

4q10, resolution 2.70Å

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