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New page: ==Crystal Structure of Lumazine Synthase from Bacillus Anthracis== <StructureSection load='4v7g' size='340' side='right' caption='4v7g, resolution 3.50Å' scene=''>...
 
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==Crystal Structure of Lumazine Synthase from Bacillus Anthracis==
==Crystal Structure of Lumazine Synthase from Bacillus Anthracis==
<StructureSection load='4v7g' size='340' side='right' caption='[[4v7g]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
<StructureSection load='4v7g' size='340' side='right'caption='[[4v7g]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4v7g]] is a 90 chain structure. This structure supersedes the now removed PDB entries and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3jv8 3jv8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V7G FirstGlance]. <br>
<table><tr><td colspan='2'>[[4v7g]] is a 90 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vsw 1vsw], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vsx 1vsx] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3jv8 3jv8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V7G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jv8|3jv8]], [[1vsw|1vsw]], [[1vsx|1vsx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6,7-dimethyl-8-ribityllumazine_synthase 6,7-dimethyl-8-ribityllumazine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.78 2.5.1.78] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v7g OCA], [https://pdbe.org/4v7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v7g RCSB], [https://www.ebi.ac.uk/pdbsum/4v7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v7g ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v7g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v7g RCSB], [http://www.ebi.ac.uk/pdbsum/4v7g PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RISB_BACAN RISB_BACAN]] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]<ref>PMID:20823551</ref>
[https://www.uniprot.org/uniprot/RISB_BACAN RISB_BACAN] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]<ref>PMID:20823551</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4v7g" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 6,7-dimethyl-8-ribityllumazine synthase]]
[[Category: Bacillus anthracis]]
[[Category: Bacher, A]]
[[Category: Large Structures]]
[[Category: Cushman, M]]
[[Category: Bacher A]]
[[Category: Fischer, M]]
[[Category: Cushman M]]
[[Category: Illarionov, B]]
[[Category: Fischer M]]
[[Category: Ladenstein, R]]
[[Category: Illarionov B]]
[[Category: Morgunova, E]]
[[Category: Ladenstein R]]
[[Category: Popov, A]]
[[Category: Morgunova E]]
[[Category: Saller, S]]
[[Category: Popov A]]
[[Category: Sambaiah, T]]
[[Category: Saller S]]
[[Category: Riboflavin biosynthesis]]
[[Category: Sambaiah T]]
[[Category: Transferase]]

Latest revision as of 18:04, 20 September 2023

Crystal Structure of Lumazine Synthase from Bacillus Anthracis

4v7g, resolution 3.50Å

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