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==Crystal Structure of Thermotoga maritima FtsH Periplasmic Domain==
==Crystal Structure of Thermotoga maritima FtsH Periplasmic Domain==
<StructureSection load='4m8a' size='340' side='right' caption='[[4m8a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4m8a' size='340' side='right'caption='[[4m8a]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4m8a]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M8A FirstGlance]. <br>
<table><tr><td colspan='2'>[[4m8a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M8A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.502&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m8a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m8a RCSB], [http://www.ebi.ac.uk/pdbsum/4m8a PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m8a OCA], [https://pdbe.org/4m8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m8a RCSB], [https://www.ebi.ac.uk/pdbsum/4m8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m8a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FTSH_THEMA FTSH_THEMA]] Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.[HAMAP-Rule:MF_01458]  
[https://www.uniprot.org/uniprot/FTSH_THEMA FTSH_THEMA] Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.[HAMAP-Rule:MF_01458]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: An, J Y]]
[[Category: Large Structures]]
[[Category: Barrera, F N]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Engelman, D M]]
[[Category: An JY]]
[[Category: Eom, S H]]
[[Category: Barrera FN]]
[[Category: Kang, G B]]
[[Category: Engelman DM]]
[[Category: Karabadzhak, A]]
[[Category: Eom SH]]
[[Category: Lee, K W]]
[[Category: Kang GB]]
[[Category: Lee, S]]
[[Category: Karabadzhak A]]
[[Category: Park, K J]]
[[Category: Lee KW]]
[[Category: Sakkiah, S]]
[[Category: Lee S]]
[[Category: Sharif, H]]
[[Category: Park KJ]]
[[Category: Wang, J]]
[[Category: Sakkiah S]]
[[Category: Atp-dependent proteolysis]]
[[Category: Sharif H]]
[[Category: Hydrolase]]
[[Category: Wang J]]
[[Category: Open-closed gating]]
[[Category: Periplasmic innermembrane]]
[[Category: Protease]]
Retrieved from "https://proteopedia.org/4m8a"