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==Mechanism of transhydrogenase coupling proton translocation and hydride transfer==
==Mechanism of transhydrogenase coupling proton translocation and hydride transfer==
<StructureSection load='4o9t' size='340' side='right' caption='[[4o9t]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
<StructureSection load='4o9t' size='340' side='right'caption='[[4o9t]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4o9t]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9T FirstGlance]. <br>
<table><tr><td colspan='2'>[[4o9t]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB27 Thermus thermophilus HB27]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O9T FirstGlance]. <br>
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(P)(+)_transhydrogenase_(Re/Si-specific) NAD(P)(+) transhydrogenase (Re/Si-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.1.2 1.6.1.2] </span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.079&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o9t RCSB], [http://www.ebi.ac.uk/pdbsum/4o9t PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9t OCA], [https://pdbe.org/4o9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o9t RCSB], [https://www.ebi.ac.uk/pdbsum/4o9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o9t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q72GS0_THET2 Q72GS0_THET2]] The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity).[PIRNR:PIRNR000204]  
[https://www.uniprot.org/uniprot/Q72GR9_THET2 Q72GR9_THET2]  
 
==See Also==
*[[NAD(P) transhydrogenase 3D structures|NAD(P) transhydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Carragher, B]]
[[Category: Large Structures]]
[[Category: Gennis, R B]]
[[Category: Thermus thermophilus HB27]]
[[Category: Leung, J H]]
[[Category: Carragher B]]
[[Category: Moeller, A]]
[[Category: Gennis RB]]
[[Category: Potter, C S]]
[[Category: Leung JH]]
[[Category: Schurig-Briccio, L A]]
[[Category: Moeller A]]
[[Category: Stout, C D]]
[[Category: Potter CS]]
[[Category: Yamaguchi, M]]
[[Category: Schurig-Briccio LA]]
[[Category: Integral membrane component of thermus thermophilus transhydrogenase]]
[[Category: Stout CD]]
[[Category: Membrane protein]]
[[Category: Yamaguchi M]]
[[Category: Nicotinamide nucleotide transhydrogenase couples the proton motive force to nadph formation]]
[[Category: Periplasmic membrane and cytosol]]
[[Category: Proton translocation and hydride transfer]]
[[Category: Respiratory enzyme]]
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