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[[Image:2cun.gif|left|200px]]


{{Structure
==Crystal structure of Phosphoglycerate Kinase from Pyrococcus horikoshii OT3==
|PDB= 2cun |SIZE=350|CAPTION= <scene name='initialview01'>2cun</scene>, resolution 2.10&Aring;
<StructureSection load='2cun' size='340' side='right'caption='[[2cun]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
<table><tr><td colspan='2'>[[2cun]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CUN FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphoglycerate_kinase Phosphoglycerate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.3 2.7.2.3]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cun OCA], [https://pdbe.org/2cun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cun RCSB], [https://www.ebi.ac.uk/pdbsum/2cun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cun ProSAT], [https://www.topsan.org/Proteins/RSGI/2cun TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PGK_PYRHO PGK_PYRHO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/2cun_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cun ConSurf].
<div style="clear:both"></div>


'''Crystal structure of Phosphoglycerate Kinase from Pyrococcus horikoshii OT3'''
==See Also==
 
*[[Phosphoglycerate kinase 3D structures|Phosphoglycerate kinase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2CUN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CUN OCA].
[[Category: Large Structures]]
[[Category: Phosphoglycerate kinase]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Pyrococcus horikoshii]]
[[Category: Kunishima N]]
[[Category: Single protein]]
[[Category: Mizutani H]]
[[Category: Kunishima, N.]]
[[Category: Mizutani, H.]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: 3PG]]
[[Category: CL]]
[[Category: GOL]]
[[Category: MPD]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: phosphoglycerate kinase]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: tanpaku 3000]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:20:00 2008''

Latest revision as of 08:20, 25 October 2023

Crystal structure of Phosphoglycerate Kinase from Pyrococcus horikoshii OT3

2cun, resolution 2.10Å

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