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==Crystal structure of the I75A mutant of human class alpha glutathione transferase in the apo form==
==Crystal structure of the I75A mutant of human class alpha glutathione transferase in the apo form==
<StructureSection load='3zfb' size='340' side='right' caption='[[3zfb]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='3zfb' size='340' side='right'caption='[[3zfb]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zfb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZFB FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zfb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZFB FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zfl|3zfl]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfb OCA], [https://pdbe.org/3zfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zfb RCSB], [https://www.ebi.ac.uk/pdbsum/3zfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zfb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zfb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zfb RCSB], [http://www.ebi.ac.uk/pdbsum/3zfb PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>
[https://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>  


==See Also==
==See Also==
*[[Glutathione S-transferase|Glutathione S-transferase]]
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Glutathione transferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Achilonu, I A]]
[[Category: Large Structures]]
[[Category: Dirr, H W]]
[[Category: Achilonu IA]]
[[Category: Fanucchi, S]]
[[Category: Dirr HW]]
[[Category: Fernandes, M A]]
[[Category: Fanucchi S]]
[[Category: Gildenhuys, S]]
[[Category: Fernandes MA]]
[[Category: Parbhoo, N]]
[[Category: Gildenhuys S]]
[[Category: Thioredoxin]]
[[Category: Parbhoo N]]
[[Category: Topologically conserved]]
[[Category: Transferase]]
[[Category: Xenobiotic detoxification]]
Retrieved from "https://proteopedia.org/3zfb"