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[[Image:2d4e.gif|left|200px]]


{{Structure
==Crystal Structure of the HpcC from Thermus Thermophilus HB8==
|PDB= 2d4e |SIZE=350|CAPTION= <scene name='initialview01'>2d4e</scene>, resolution 2.10&Aring;
<StructureSection load='2d4e' size='340' side='right'caption='[[2d4e]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2d4e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D4E FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/5-carboxymethyl-2-hydroxymuconic-semialdehyde_dehydrogenase 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.60 1.2.1.60]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
|GENE=
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4e OCA], [https://pdbe.org/2d4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d4e RCSB], [https://www.ebi.ac.uk/pdbsum/2d4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d4e ProSAT], [https://www.topsan.org/Proteins/RSGI/2d4e TOPSAN]</span></td></tr>
 
</table>
'''Crystal Structure of the HpcC from Thermus Thermophilus HB8'''
== Function ==
 
[https://www.uniprot.org/uniprot/Q5SJP9_THET8 Q5SJP9_THET8]  
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2D4E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4E OCA].
Check<jmol>
[[Category: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/2d4e_consurf.spt"</scriptWhenChecked>
[[Category: Thermus thermophilus]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Kunishima, N.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Mizutani, H.]]
  </jmolCheckbox>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d4e ConSurf].
[[Category: GOL]]
<div style="clear:both"></div>
[[Category: NA]]
__TOC__
[[Category: NAD]]
</StructureSection>
[[Category: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase]]
[[Category: Large Structures]]
[[Category: hpcc]]
[[Category: Thermus thermophilus HB8]]
[[Category: national project on protein structural and functional analyse]]
[[Category: Kunishima N]]
[[Category: nppsfa]]
[[Category: Mizutani H]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:23:15 2008''

Latest revision as of 08:24, 25 October 2023

Crystal Structure of the HpcC from Thermus Thermophilus HB8

2d4e, resolution 2.10Å

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