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==Structure of small TOPRIM domain protein from Bacillus stearothermophilus.==
==Structure of small TOPRIM domain protein from Bacillus stearothermophilus.==
<StructureSection load='2fcj' size='340' side='right' caption='[[2fcj]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='2fcj' size='340' side='right'caption='[[2fcj]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2fcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FCJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2fcj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FCJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RBSTP2199 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fcj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fcj RCSB], [http://www.ebi.ac.uk/pdbsum/2fcj PDBsum], [http://www.topsan.org/Proteins/MCSG/2fcj TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fcj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fcj OCA], [https://pdbe.org/2fcj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fcj RCSB], [https://www.ebi.ac.uk/pdbsum/2fcj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fcj ProSAT], [https://www.topsan.org/Proteins/MCSG/2fcj TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5KVJ9_GEOKA Q5KVJ9_GEOKA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/2fcj_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/2fcj_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fcj ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2fcj" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Acetylcholinesterase with OTMA|Acetylcholinesterase with OTMA]]
*[[Central glycolytic gene regulator (CggR)|Central glycolytic gene regulator (CggR)]]
*[[Acid beta-glucosidase with N-butyl-deoxynojirimycin|Acid beta-glucosidase with N-butyl-deoxynojirimycin]]
*[[TOPRIM domain protein|TOPRIM domain protein]]
*[[TOPRIM domain protein|TOPRIM domain protein]]
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Borek, D]]
[[Category: Large Structures]]
[[Category: Chen, Y]]
[[Category: Borek D]]
[[Category: Collart, F]]
[[Category: Chen Y]]
[[Category: Joachimiak, A]]
[[Category: Collart F]]
[[Category: Structural genomic]]
[[Category: Joachimiak A]]
[[Category: Otwinowski, Z]]
[[Category: Otwinowski Z]]
[[Category: Rezacova, P]]
[[Category: Rezacova P]]
[[Category: Mcsg]]
[[Category: PSI, Protein structure initiative]]
[[Category: Toprim domain]]
[[Category: Unknown function]]