2d9e: Difference between revisions

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[[Image:2d9e.gif|left|200px]]


{{Structure
==Solution structure of the Bromodomain of Peregrin==
|PDB= 2d9e |SIZE=350|CAPTION= <scene name='initialview01'>2d9e</scene>
<StructureSection load='2d9e' size='340' side='right'caption='[[2d9e]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2d9e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D9E FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= BRPF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d9e OCA], [https://pdbe.org/2d9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d9e RCSB], [https://www.ebi.ac.uk/pdbsum/2d9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d9e ProSAT], [https://www.topsan.org/Proteins/RSGI/2d9e TOPSAN]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/2d9e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d9e ConSurf].
<div style="clear:both"></div>


'''Solution structure of the Bromodomain of Peregrin'''
==See Also==
 
*[[Peregrin|Peregrin]]
 
== References ==
==About this Structure==
<references/>
2D9E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D9E OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hatta, R.]]
[[Category: Hatta R]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Izumi, K.]]
[[Category: Izumi K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoshida M]]
[[Category: Yoshida, M.]]
[[Category: four-helix bundle]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription activator]]
 
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Retrieved from "https://proteopedia.org/2d9e"