2dt5: Difference between revisions

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[[Image:2dt5.jpg|left|200px]]


{{Structure
==Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8==
|PDB= 2dt5 |SIZE=350|CAPTION= <scene name='initialview01'>2dt5</scene>, resolution 2.16&Aring;
<StructureSection load='2dt5' size='340' side='right'caption='[[2dt5]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
<table><tr><td colspan='2'>[[2dt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DT5 FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.16&#8491;</td></tr>
|GENE= TTHA1657 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dt5 OCA], [https://pdbe.org/2dt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2dt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dt5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dt5 TOPSAN]</span></td></tr>
 
</table>
'''Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8'''
== Function ==
 
[https://www.uniprot.org/uniprot/REX_THET8 REX_THET8] Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.[HAMAP-Rule:MF_01131]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2DT5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DT5 OCA].
Check<jmol>
 
  <jmolCheckbox>
==Reference==
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dt/2dt5_consurf.spt"</scriptWhenChecked>
Crystal structure of TTHA1657 (AT-rich DNA-binding protein; p25) from Thermus thermophilus HB8 at 2.16 A resolution., Nakamura A, Sosa A, Komori H, Kita A, Miki K, Proteins. 2007 Feb 15;66(3):755-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17154156 17154156]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Single protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Thermus thermophilus]]
  </jmolCheckbox>
[[Category: Kita, A.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dt5 ConSurf].
[[Category: Komori, H.]]
<div style="clear:both"></div>
[[Category: Miki, K.]]
__TOC__
[[Category: Nakamura, A.]]
</StructureSection>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Large Structures]]
[[Category: Sosa, A.]]
[[Category: Thermus thermophilus HB8]]
[[Category: CL]]
[[Category: Kita A]]
[[Category: GOL]]
[[Category: Komori H]]
[[Category: NAD]]
[[Category: Miki K]]
[[Category: SO4]]
[[Category: Nakamura A]]
[[Category: nad]]
[[Category: Sosa A]]
[[Category: nadh]]
[[Category: redox sensing]]
[[Category: rex]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rossmann fold]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: thermus themophilus]]
[[Category: winged helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:31:15 2008''

Latest revision as of 18:46, 29 May 2024

Crystal Structure of TTHA1657 (AT-rich DNA-binding protein) from Thermus thermophilus HB8

2dt5, resolution 2.16Å

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