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==Crystal structure of PAS domain of S. aureus YycG==
==Crystal structure of PAS domain of S. aureus YycG==
<StructureSection load='4mn5' size='340' side='right' caption='[[4mn5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4mn5' size='340' side='right'caption='[[4mn5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mn5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MN5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MN5 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mn5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MN5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mn6|4mn6]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mn5 OCA], [https://pdbe.org/4mn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mn5 RCSB], [https://www.ebi.ac.uk/pdbsum/4mn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mn5 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mn5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mn5 RCSB], [http://www.ebi.ac.uk/pdbsum/4mn5 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/WALK_STAAU WALK_STAAU]] Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR (By similarity).  
[https://www.uniprot.org/uniprot/WALK_STAAU WALK_STAAU] Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Histidine kinase]]
[[Category: Large Structures]]
[[Category: Collins, B M]]
[[Category: Staphylococcus aureus]]
[[Category: Hvorup, R]]
[[Category: Collins BM]]
[[Category: King, G F]]
[[Category: Hvorup R]]
[[Category: Shaikh, N]]
[[Category: King GF]]
[[Category: Winnen, B]]
[[Category: Shaikh N]]
[[Category: Pas domain]]
[[Category: Winnen B]]
[[Category: Transferase]]

Latest revision as of 07:11, 27 November 2024

Crystal structure of PAS domain of S. aureus YycG

4mn5, resolution 2.00Å

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