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==Crystal Structure of the Plectin 1 and 2 Repeats of the Human Periplakin. Northeast Structural Genomics Consortium (NESG) Target HR9083A==
==Crystal Structure of the Plectin 1 and 2 Repeats of the Human Periplakin. Northeast Structural Genomics Consortium (NESG) Target HR9083A==
<StructureSection load='4q28' size='340' side='right' caption='[[4q28]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
<StructureSection load='4q28' size='340' side='right'caption='[[4q28]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4q28]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q28 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q28 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4q28]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Q28 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q28 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q28 RCSB], [http://www.ebi.ac.uk/pdbsum/4q28 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4q28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q28 OCA], [https://pdbe.org/4q28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4q28 RCSB], [https://www.ebi.ac.uk/pdbsum/4q28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4q28 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PEPL_HUMAN PEPL_HUMAN]] Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling.<ref>PMID:9412476</ref> 
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acton, T B]]
[[Category: Homo sapiens]]
[[Category: Connell, P T.O]]
[[Category: Large Structures]]
[[Category: Everett, J K]]
[[Category: Acton TB]]
[[Category: Hunt, J F]]
[[Category: Everett JK]]
[[Category: Janjua, H]]
[[Category: Hunt JF]]
[[Category: Lew, S]]
[[Category: Janjua H]]
[[Category: Maglaqui, M]]
[[Category: Lew S]]
[[Category: Montelione, G T]]
[[Category: Maglaqui M]]
[[Category: Structural genomic]]
[[Category: Montelione GT]]
[[Category: Seetharaman, J]]
[[Category: O'Connell PT]]
[[Category: Tong, L]]
[[Category: Seetharaman J]]
[[Category: Vorobiev, S]]
[[Category: Tong L]]
[[Category: Wang, D]]
[[Category: Vorobiev S]]
[[Category: Xiao, R]]
[[Category: Wang D]]
[[Category: Nesg]]
[[Category: Xiao R]]
[[Category: Periplakin]]
[[Category: Plectin]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Structural protein]]

Latest revision as of 03:27, 21 November 2024

Crystal Structure of the Plectin 1 and 2 Repeats of the Human Periplakin. Northeast Structural Genomics Consortium (NESG) Target HR9083A

4q28, resolution 2.64Å

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