4liy: Difference between revisions

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==Structure of the adenovirus 3 knob domain K217E and F224S mutant==
==Structure of the adenovirus 3 knob domain K217E and F224S mutant==
<StructureSection load='4liy' size='340' side='right' caption='[[4liy]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4liy' size='340' side='right'caption='[[4liy]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4liy]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LIY FirstGlance]. <br>
<table><tr><td colspan='2'>[[4liy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_B3 Human adenovirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h7z|1h7z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4liy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4liy RCSB], [http://www.ebi.ac.uk/pdbsum/4liy PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4liy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liy OCA], [https://pdbe.org/4liy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4liy RCSB], [https://www.ebi.ac.uk/pdbsum/4liy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4liy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.  
[https://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4liy" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fender, P]]
[[Category: Human adenovirus B3]]
[[Category: Zubieta, C]]
[[Category: Large Structures]]
[[Category: Adenovirus fibre protein knob domain]]
[[Category: Fender P]]
[[Category: Desmoglein 2]]
[[Category: Zubieta C]]
[[Category: Receptor interaction]]
[[Category: Viral attachment to host cell]]
[[Category: Viral protein]]