3zm6: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(3 intermediate revisions by the same user not shown)
Line 1: Line 1:
==CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR==
==CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR==
<StructureSection load='3zm6' size='340' side='right' caption='[[3zm6]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
<StructureSection load='3zm6' size='340' side='right'caption='[[3zm6]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zm6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_r6 Streptococcus pneumoniae r6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZM6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zm6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZM6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZM6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2GN:N-(6-(4-(2H-TETRAZOL-5-YL)BENZYL)-3-CYANO-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDIN-2-YL)-2,4-DICHLORO-5-(MORPHOLINOSULFONYL)BENZAMIDE'>2GN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zl8|3zl8]], [[3zm5|3zm5]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2GN:N-(6-(4-(2H-TETRAZOL-5-YL)BENZYL)-3-CYANO-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDIN-2-YL)-2,4-DICHLORO-5-(MORPHOLINOSULFONYL)BENZAMIDE'>2GN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine_ligase UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.10 6.3.2.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zm6 OCA], [https://pdbe.org/3zm6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zm6 RCSB], [https://www.ebi.ac.uk/pdbsum/3zm6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zm6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zm6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zm6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zm6 RCSB], [http://www.ebi.ac.uk/pdbsum/3zm6 PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q8DNV6_STRR6 Q8DNV6_STRR6]] Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity).[RuleBase:RU004136]  
[https://www.uniprot.org/uniprot/Q8DNV6_STRR6 Q8DNV6_STRR6] Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity).[RuleBase:RU004136]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3zm6" style="background-color:#fffaf0;"></div>
==See Also==
*[[Mur ligase|Mur ligase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptococcus pneumoniae r6]]
[[Category: Large Structures]]
[[Category: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase]]
[[Category: Streptococcus pneumoniae R6]]
[[Category: Barreteau, H]]
[[Category: Barreteau H]]
[[Category: Blanot, D]]
[[Category: Blanot D]]
[[Category: Contreras-Martel, C]]
[[Category: Contreras-Martel C]]
[[Category: Dessen, A]]
[[Category: Dessen A]]
[[Category: Gobec, S]]
[[Category: Gobec S]]
[[Category: Hrast, M]]
[[Category: Hrast M]]
[[Category: Knez, D]]
[[Category: Knez D]]
[[Category: Mengin-Lecreulx, D]]
[[Category: Mengin-Lecreulx D]]
[[Category: ONeill, A J]]
[[Category: ONeill AJ]]
[[Category: Randall, C P]]
[[Category: Randall CP]]
[[Category: Sosic, I]]
[[Category: Sosic I]]
[[Category: Turk, S]]
[[Category: Turk S]]
[[Category: Adp-forming enzyme]]
[[Category: Atp-binding]]
[[Category: Cell cycle]]
[[Category: Cell divison]]
[[Category: Cell shape]]
[[Category: Cell wall]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Peptidoglycan synthesis]]
Retrieved from "https://proteopedia.org/3zm6"