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New page: left|200px {{Structure |PDB= 2eiy |SIZE=350|CAPTION= <scene name='initialview01'>2eiy</scene>, resolution 1.35Å |SITE= <scene name='pdbsite=AC1:Plp+Binding+Site+...
 
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{{Structure
==Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase Complexed with 4-Methylvaleric Acid==
|PDB= 2eiy |SIZE=350|CAPTION= <scene name='initialview01'>2eiy</scene>, resolution 1.35&Aring;
<StructureSection load='2eiy' size='340' side='right'caption='[[2eiy]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Plp+Binding+Site+For+Residue+A+413'>AC1</scene>, <scene name='pdbsite=AC2:Plp+Binding+Site+For+Residue+B+913'>AC2</scene>, <scene name='pdbsite=AC3:Plp+Binding+Site+For+Residue+C+1413'>AC3</scene>, <scene name='pdbsite=AC4:4mv+Binding+Site+For+Residue+A+2414'>AC4</scene>, <scene name='pdbsite=AC5:4mv+Binding+Site+For+Residue+B+914'>AC5</scene>, <scene name='pdbsite=AC6:4mv+Binding+Site+For+Residue+C+1414'>AC6</scene>, <scene name='pdbsite=AC7:Mpd+Binding+Site+For+Residue+A+2416'>AC7</scene>, <scene name='pdbsite=AC8:Mpd+Binding+Site+For+Residue+A+2417'>AC8</scene>, <scene name='pdbsite=AC9:Mpd+Binding+Site+For+Residue+B+915'>AC9</scene>, <scene name='pdbsite=BC1:Mpd+Binding+Site+For+Residue+B+917'>BC1</scene> and <scene name='pdbsite=BC2:Mpd+Binding+Site+For+Residue+C+1416'>BC2</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=PLP:PYRIDOXAL-5'-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=4MV:4-METHYL+VALERIC+ACID'>4MV</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
<table><tr><td colspan='2'>[[2eiy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EIY FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4MV:4-METHYL+VALERIC+ACID'>4MV</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eiy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eiy OCA], [https://pdbe.org/2eiy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eiy RCSB], [https://www.ebi.ac.uk/pdbsum/2eiy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eiy ProSAT], [https://www.topsan.org/Proteins/RSGI/2eiy TOPSAN]</span></td></tr>
 
</table>
'''Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase Complexed with 4-Methylvaleric Acid'''
== Function ==
 
[https://www.uniprot.org/uniprot/Q5SM19_THET8 Q5SM19_THET8]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2EIY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EIY OCA].  
Check<jmol>
[[Category: Branched-chain-amino-acid transaminase]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ei/2eiy_consurf.spt"</scriptWhenChecked>
[[Category: Thermus thermophilus]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Goto, M.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: 4MV]]
  </jmolCheckbox>
[[Category: MPD]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eiy ConSurf].
[[Category: PLP]]
<div style="clear:both"></div>
[[Category: plp-dependent enzyme]]
__TOC__
[[Category: transferase]]
</StructureSection>
 
[[Category: Large Structures]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:40:50 2008''
[[Category: Thermus thermophilus HB8]]
[[Category: Goto M]]
Retrieved from "https://proteopedia.org/2eiy"