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New page: left|200px {{Structure |PDB= 2ej2 |SIZE=350|CAPTION= <scene name='initialview01'>2ej2</scene>, resolution 2.00Å |SITE= <scene name='pdbsite=AC1:Ppe+Binding+Site+...
 
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[[Image:2ej2.jpg|left|200px]]
==Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase Complexed with N-(5'-Phosphopyridoxyl)-L-Glutamate==
 
<StructureSection load='2ej2' size='340' side='right' caption='[[2ej2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
{{Structure
== Structural highlights ==
|PDB= 2ej2 |SIZE=350|CAPTION= <scene name='initialview01'>2ej2</scene>, resolution 2.00&Aring;
<table><tr><td colspan='2'>[[2ej2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EJ2 FirstGlance]. <br>
|SITE= <scene name='pdbsite=AC1:Ppe+Binding+Site+For+Residue+A+3413'>AC1</scene>, <scene name='pdbsite=AC2:Ppe+Binding+Site+For+Residue+B+3913'>AC2</scene>, <scene name='pdbsite=AC3:Ppe+Binding+Site+For+Residue+C+1413'>AC3</scene>, <scene name='pdbsite=AC4:Ppe+Binding+Site+For+Residue+D+1913'>AC4</scene>, <scene name='pdbsite=AC5:Ppe+Binding+Site+For+Residue+E+2413'>AC5</scene>, <scene name='pdbsite=AC6:Ppe+Binding+Site+For+Residue+F+2913'>AC6</scene>, <scene name='pdbsite=AC7:Mpd+Binding+Site+For+Residue+A+1415'>AC7</scene> and <scene name='pdbsite=AC8:Mpd+Binding+Site+For+Residue+F+2914'>AC8</scene>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PPE:4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM'>PPE</scene></td></tr>
|LIGAND= <scene name='pdbligand=PPE:4-[(1,3-DICARBOXY-PROPYLAMINO)-METHYL]-3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDINIUM'>PPE</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2eiy|2eiy]], [[2ej0|2ej0]], [[2ej3|2ej3]]</td></tr>
|ACTIVITY= [http://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42]  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Branched-chain-amino-acid_transaminase Branched-chain-amino-acid transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.42 2.6.1.42] </span></td></tr>
|GENE=  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ej2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ej2 OCA], [http://pdbe.org/2ej2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ej2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ej2 PDBsum], [http://www.topsan.org/Proteins/RSGI/2ej2 TOPSAN]</span></td></tr>
}}
</table>
 
== Evolutionary Conservation ==
'''Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase Complexed with N-(5'-Phosphopyridoxyl)-L-Glutamate'''
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
 
  <jmolCheckbox>
==About this Structure==
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ej/2ej2_consurf.spt"</scriptWhenChecked>
2EJ2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EJ2 OCA].  
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ej2 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Branched-chain-amino-acid transaminase]]
[[Category: Single protein]]
[[Category: Thet8]]
[[Category: Thermus thermophilus]]
[[Category: Goto, M]]
[[Category: Goto, M.]]
[[Category: Plp-dependent enzyme]]
[[Category: MPD]]
[[Category: Transferase]]
[[Category: PPE]]
[[Category: plp-dependent enzyme]]
[[Category: transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:40:58 2008''

Latest revision as of 19:46, 9 February 2016

Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase Complexed with N-(5'-Phosphopyridoxyl)-L-Glutamate

2ej2, resolution 2.00Å

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