2eo0: Difference between revisions
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==Crystal Structure of Holliday Junction Resolvase ST1444== | |||
<StructureSection load='2eo0' size='340' side='right'caption='[[2eo0]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2eo0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurisphaera_tokodaii_str._7 Sulfurisphaera tokodaii str. 7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EO0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EO0 FirstGlance]. <br> | |||
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eo0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eo0 OCA], [https://pdbe.org/2eo0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eo0 RCSB], [https://www.ebi.ac.uk/pdbsum/2eo0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eo0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2eo0 TOPSAN]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HJC_SULTO HJC_SULTO] A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Inhibits the helicase activity of Hel308 (Hjm).[HAMAP-Rule:MF_01490]<ref>PMID:18296528</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eo0_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eo0 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Resolvase 3D structures|Resolvase 3D structures]] | |||
== References == | |||
== | <references/> | ||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Kagawa | [[Category: Sulfurisphaera tokodaii str. 7]] | ||
[[Category: Kurumizaka | [[Category: Kagawa W]] | ||
[[Category: Kurumizaka H]] | |||
[[Category: Sarai | [[Category: Sarai N]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||
Latest revision as of 08:43, 25 October 2023
Crystal Structure of Holliday Junction Resolvase ST1444
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