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==The 1.1 Angstrom Structure of Catalytic Core Domain of FIV Integrase==
==The 1.1 Angstrom Structure of Catalytic Core Domain of FIV Integrase==
<StructureSection load='4mq3' size='340' side='right' caption='[[4mq3]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
<StructureSection load='4mq3' size='340' side='right'caption='[[4mq3]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4mq3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MQ3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4mq3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus_(isolate_Petaluma) Feline immunodeficiency virus (isolate Petaluma)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MQ3 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mq3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mq3 RCSB], [http://www.ebi.ac.uk/pdbsum/4mq3 PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mq3 OCA], [https://pdbe.org/4mq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mq3 RCSB], [https://www.ebi.ac.uk/pdbsum/4mq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mq3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE]] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.  
[https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4mq3" style="background-color:#fffaf0;"></div>
==See Also==
*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alian, A]]
[[Category: Large Structures]]
[[Category: Galilee, M]]
[[Category: Alian A]]
[[Category: Alpha beta]]
[[Category: Galilee M]]
[[Category: Nucleotidyltransferase]]
[[Category: Ribonuclease-h like motif]]
[[Category: Viral protein]]
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