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==STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF PARTNER SWITCHING REGULATING THE ENVIRONMENTAL STRESS RESPONSE IN BACILLUS SUBTILIS==
 
<StructureSection load='2j6y' size='340' side='right' caption='[[2j6y]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
==Structural and Functional Characterisation of partner switching regulating the environmental stress response in Bacillus subtilis==
<StructureSection load='2j6y' size='340' side='right'caption='[[2j6y]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2j6y]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J6Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J6Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[2j6y]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J6Y FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w53|1w53]], [[2j6z|2j6z]], [[2j70|2j70]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoserine_phosphatase Phosphoserine phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.3 3.1.3.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j6y OCA], [https://pdbe.org/2j6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j6y RCSB], [https://www.ebi.ac.uk/pdbsum/2j6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j6y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j6y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j6y RCSB], [http://www.ebi.ac.uk/pdbsum/2j6y PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RSBU_BACSU RSBU_BACSU]] Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module.<ref>PMID:8824586</ref>
[https://www.uniprot.org/uniprot/RSBU_BACSU RSBU_BACSU] Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module.<ref>PMID:8824586</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j6/2j6y_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j6/2j6y_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j6y ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2j6y" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Phosphoserine phosphatase]]
[[Category: Large Structures]]
[[Category: Delumeau, O]]
[[Category: Delumeau O]]
[[Category: Hardwick, S W]]
[[Category: Hardwick SW]]
[[Category: Hecker, M]]
[[Category: Hecker M]]
[[Category: Lewis, R J]]
[[Category: Lewis RJ]]
[[Category: Marles-Wright, J]]
[[Category: Marles-Wright J]]
[[Category: Murray, J W]]
[[Category: Murray JW]]
[[Category: Pane-Farre, J]]
[[Category: Pane-Farre J]]
[[Category: Bacillus subtili]]
[[Category: Hydrolase]]
[[Category: Partner switching]]
[[Category: Protein phosphatase]]
[[Category: Rsbt]]
[[Category: Rsbu]]
[[Category: Stress]]