2f0z: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (12 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor== | |||
<StructureSection load='2f0z' size='340' side='right'caption='[[2f0z]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
| | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2f0z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0Z FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
| | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZMR:ZANAMIVIR'>ZMR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0z OCA], [https://pdbe.org/2f0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0z RCSB], [https://www.ebi.ac.uk/pdbsum/2f0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0z ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/2f0z_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f0z ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]] | |||
__TOC__ | |||
== | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Chavas | [[Category: Chavas LMG]] | ||
[[Category: Colman | [[Category: Colman PM]] | ||
[[Category: Fusi | [[Category: Fusi P]] | ||
[[Category: Kato | [[Category: Kato R]] | ||
[[Category: McKimm-Breschkin | [[Category: McKimm-Breschkin J]] | ||
[[Category: Monti | [[Category: Monti E]] | ||
[[Category: Tettamanti | [[Category: Tettamanti G]] | ||
[[Category: Tringali | [[Category: Tringali C]] | ||
[[Category: Venerando | [[Category: Venerando B]] | ||
[[Category: Wakatsuki | [[Category: Wakatsuki S]] | ||
Latest revision as of 08:44, 25 October 2023
Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor
| ||||||||||||
