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==Icosahedral particle of covalent coat protein dimer of bacteriophage MS2==
==Icosahedral particle of covalent coat protein dimer of bacteriophage MS2==
<StructureSection load='2wbh' size='340' side='right' caption='[[2wbh]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
<StructureSection load='2wbh' size='340' side='right'caption='[[2wbh]], [[Resolution|resolution]] 4.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2wbh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpms2 Bpms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBH FirstGlance]. <br>
<table><tr><td colspan='2'>[[2wbh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_MS2 Escherichia virus MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b2e|2b2e]], [[6msf|6msf]], [[2bs0|2bs0]], [[2iz9|2iz9]], [[7msf|7msf]], [[2b2g|2b2g]], [[2c4q|2c4q]], [[2c4y|2c4y]], [[1zdj|1zdj]], [[2c4z|2c4z]], [[2c51|2c51]], [[2bny|2bny]], [[1u1y|1u1y]], [[2vtu|2vtu]], [[2bs1|2bs1]], [[1msc|1msc]], [[1mvb|1mvb]], [[2izn|2izn]], [[1mst|1mst]], [[1aq4|1aq4]], [[2ms2|2ms2]], [[2c50|2c50]], [[1zdi|1zdi]], [[1zdk|1zdk]], [[1aq3|1aq3]], [[1mva|1mva]], [[5msf|5msf]], [[2b2d|2b2d]], [[1bms|1bms]], [[1zdh|1zdh]], [[1zse|1zse]], [[2bq5|2bq5]], [[2iz8|2iz8]], [[2izm|2izm]], [[2bu1|2bu1]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 4.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbh RCSB], [http://www.ebi.ac.uk/pdbsum/2wbh PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbh OCA], [https://pdbe.org/2wbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbh RCSB], [https://www.ebi.ac.uk/pdbsum/2wbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.  
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2wbh" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bpms2]]
[[Category: Escherichia virus MS2]]
[[Category: Liljas, L]]
[[Category: Large Structures]]
[[Category: Plevka, P]]
[[Category: Liljas L]]
[[Category: Tars, K]]
[[Category: Plevka P]]
[[Category: Capsid protein]]
[[Category: Tars K]]
[[Category: Covalent dimer]]
[[Category: Rna-binding]]
[[Category: Virion]]
[[Category: Virus]]
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